Semi-nonparametric modeling of topological domain formation from epigenetic data
نویسندگان
چکیده
منابع مشابه
Semi-nonparametric Modeling of Topological Domain Formation from Epigenetic Data
Hi-C experiments capturing the 3D genome architecture have led to the discovery of topologically-associated domains (TADs) that form an important part of the 3D genome organization and appear to play a role in gene regulation and other functions. Several histone modifications have been independently suggested as the possible explanations of TAD formation, but their combinatorial effects on doma...
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ژورنال
عنوان ژورنال: Algorithms for Molecular Biology
سال: 2019
ISSN: 1748-7188
DOI: 10.1186/s13015-019-0142-y